cis-Capsaicin is being used as tools in neurobiological research. cis-Capsaicin is used for the treatment of primary or recurrent herpes, as a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain.
Medicinal and Cosmetic Applications
Cis-capsaicin is used in dermal patches, topical ointments, and creams to relieve minor aches and pains of muscles and joints. It has been reported that a single, hour-long application of a high-concentration capsaicin skin patch provided an average of 19 weeks of sustained reduction in the pain of neuralgia. In fact, one-eighth of the patients in a year-long multicenter, double-blind, randomized clinical trial of a dermal patch experienced such durable pain relief that they never required re-treatment. The others obtained a year of substantial pain relief with four 1-hour dermal applications of the capsaicin patch.
Concentrations are typically between 0.025% and 0.075%. Research suggests that capsaicin is able to kill prostate cancer cells. The studies showed tumors treated with capsaicin were about one-fifth the size of the untreated tumors. One study suggests capsaicin may be effective against lung cancer cells and researchers in Canada are testing capsaicin as a cure for diabetes.
Food and Beverage Applications
Recently, capsaicin has been added to beverages to ‘spice’ them up. Because of the high purity, cis-Capsicin is well-suited for human consumption.