Aversion Technologies, Inc.

Protecting People, Pets and Plants


andrographolide (natural)

Andrographolide is an extract from the stem and leaves of the andrographis paniculata. Andrographolide is an extremely bitter substance, and a natural bitterant. The plant is grown for medicinal purposes in China and India, and is being used as a homeopathic treatment for stomach disorders in the United States. Andrographolide has been shown to be effective against certain cancers and is a powerful purgative. When in bloom, Andrographis exhibits small white flowers.


Andrographolide, the bitter constituent of andrographis panaculata, is believed to have stimulate the immune system, act as an anti-inflammatory, and provide liver protection. Some of the health benefits of attributed to andrographolide include:
-- Kills intestinal worms and supports intestines
-- Protects skin from pimples
-- Pain killer
-- Reduces swelling and cuts down exudation from capillaries
-- Pain killer
-- Fights bacterial activity
-- Reduces diarrhea and symptoms arising from bacterial infections
-- Promotes mucus discharge from the respiratory system
-- Blood sugar reducer
Trials have found that andrographolide can help reduce symptom severity in people with common colds. Andrographolide also said to decrease fertility.


Andrographolide may also be used as an all-natural substitute for chemical bitterants such as denatonium benzoate or denatonium saccharide. Because andrographolide is not readily soluble, it is difficult to add to.



Appearance: Brownish-yellow powder 
Loss on drying: 5.0% max 
Ash: 6.0% max
Chloride: 80ppm max
Heavy Metals: 20ppm max

Andrographolide is a lipophilic compound, which refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane, toluene, DMSO, chloroform or methanol.